Discounted Hotels & Accommodations in Cairo, IL

Cairo, IL, USAdd DatesChange Search

Destination: Cairo, IL, US(change)

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2 adults

0 children

1 room

Groups: Need 5+ Rooms?

50 Available Cairo Hotels
Rates Starting at just $54.99
24 Chains To Choose From
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Quality Inn Cairo I 57

$75

Good 3.5 65 Reviews

13201 Kessler Road Cairo, IL

Pet Friendly

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Comfort Inn & Suites Sikeston I 55

$93

Good 3.5 130 Reviews

109 Matthews Ln Sikeston, MO

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Best Western Plus Sikeston

$99

Very Good 4.5 409 Reviews

120 South Interstate Drive Sikeston, MO

Pet Friendly

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Drury Inn Paducah

$124

Very Good 4.5 446 Reviews

3975 Hinkleville Rd Paducah, KY

Pet Friendly

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Drury Inn & Suites Sikeston MO

$129

Very Good 4.5 445 Reviews

2608 East Malone Ave Sikeston, MO

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Comfort Inn Paducah I 24

$112

Very Good 4.0 419 Reviews

5135 Cairo Rd Paducah, KY

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Quality Suites

$104

0 Reviews

2880 James Sanders Blvd Paducah, KY

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Baymont by Wyndham Metropolis

$60

Good 3.0 626 Reviews

203 East Front St Metropolis, IL

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Drury Inn & Suites Paducah

$134

Very Good 4.5 442 Reviews

2930 James Sanders Blvd Paducah, KY

Pet Friendly

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Super 8 by Wyndham Sikeston / Miner Area

$86

Good 3.0 355 Reviews

2609 East Malone Ave Sikeston, MO

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