Find the Best Accommodations in Cairo, IL

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Cairo, IL, USAdd DatesChange Search
Destination: Cairo, IL, US(change)
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  • 50 Available Cairo Hotels
  • Rates Starting at just $51.87
  • 23 Chains To Choose From
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Quality Inn Cairo I-57
$74
starstar
Good 3.5   65 Reviews
13201 Kessler Road Cairo, IL
  • Pet Friendly
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Quality Inn
$100
starstar
0 Reviews
13201 Kessler Road Cairo, IL
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Comfort Inn & Suites Sikeston I-55
$92
starstar
Good 3.5   130 Reviews
109 Matthews Ln Sikeston, MO
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Best Western Plus Sikeston
$101
starstar
Very Good 4.5   409 Reviews
120 South Interstate Drive Sikeston, MO
  • Pet Friendly
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Drury Inn & Suites Sikeston MO
$118
starstarstar
Very Good 4.5   445 Reviews
2608 East Malone Ave Sikeston, MO
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Comfort Inn Paducah I-24
$91
starstar
Very Good 4.0   419 Reviews
5135 Cairo Rd Paducah, KY
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Quality Suites
$78
starstar
0 Reviews
2880 James Sanders Boulevard Paducah, KY
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Baymont by Wyndham Metropolis
$59
starstar
Good 3.0   626 Reviews
203 East Front St Metropolis, IL
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Drury Inn & Suites Paducah
$126
starstarstar
Very Good 4.5   442 Reviews
2930 James Sanders Blvd Paducah, KY
  • Pet Friendly
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Super 8 by Wyndham Sikeston / Miner Area
$61
starstar
Good 3.0   355 Reviews
2609 East Malone Ave Sikeston, MO
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